Connection | Profiles RNS

Search Result Details

Back to Search Results

This page shows the details of why an item matched the keywords from your search.

Search Results

WIERDA, WILLIAM G

One or more keywords matched the following items that are connected to WIERDA, WILLIAM G

Item Type	Name
Academic Article	Multiple-dose granulocyte-macrophage-colony-stimulating factor plus 23-valent polysaccharide pneumococcal vaccine in patients with chronic lymphocytic leukemia: a prospective, randomized trial of safety and immunogenicity.
Academic Article	HLA homozygosity and haplotype bias among patients with chronic lymphocytic leukemia: implications for disease control by physiological immune surveillance.
Academic Article	Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia.
Academic Article	Phase II study of alemtuzumab in combination with pentostatin in patients with T-cell neoplasms.
Academic Article	The great imitator: systemic nocardiosis mimicking Richter's transformation in relapsed chronic lymphocytic leukemia.
Concept	Leukemia, Hairy Cell
Concept	Leukemia, T-Cell
Concept	Leukemia, B-Cell
Academic Article	Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach.
Academic Article	B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.
Academic Article	Impaired bactericidal but not fungicidal activity of polymorphonuclear neutrophils in patients with chronic lymphocytic leukemia.
Academic Article	Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia.
Academic Article	Phase I-II clinical trial of oxaliplatin, fludarabine, cytarabine, and rituximab therapy in aggressive relapsed/refractory chronic lymphocytic leukemia or Richter syndrome.
Academic Article	Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.
Academic Article	Chronic lymphocytic leukemia.
Academic Article	Eradication of minimal residual disease in hairy cell leukemia.
Academic Article	T-cell large granular lymphocytic (T-LGL) leukemia: experience in a single institution over 8 years.
Academic Article	The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy.
Academic Article	Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia.
Academic Article	High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation.
Academic Article	Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells.
Academic Article	Eltrombopag, a second-generation thrombopoietin receptor agonist, for chronic lymphocytic leukemia-associated ITP.
Academic Article	Phase I and pharmacologic study of SNS-032, a potent and selective Cdk2, 7, and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia and multiple myeloma.
Academic Article	Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression.
Academic Article	Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Cyclophosphamide, fludarabine, alemtuzumab, and rituximab as salvage therapy for heavily pretreated patients with chronic lymphocytic leukemia.
Academic Article	Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia.
Academic Article	Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells.
Academic Article	CARs in chronic lymphocytic leukemia -- ready to drive.
Academic Article	Genomic variation by whole-genome SNP mapping arrays predicts time-to-event outcome in patients with chronic lymphocytic leukemia: a comparison of CLL and HapMap genotypes.
Academic Article	Lenalidomide-induced graft-vs.-Leukemia effect in a patient with chronic lymphocytic leukemia who relapsed after allogeneic stem cell transplant.
Academic Article	High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia.
Academic Article	Immunologic monitoring in chronic lymphocytic leukemia.
Academic Article	Fludarabine and mitoxantrone for patients with chronic lymphocytic leukemia.
Academic Article	Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins.
Academic Article	Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia.
Academic Article	Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia.
Academic Article	Novel immune-based treatment strategies for chronic lymphocytic leukemia.
Academic Article	Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine.
Academic Article	Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia.
Academic Article	Identification and validation of biomarkers of IgV(H) mutation status in chronic lymphocytic leukemia using microfluidics quantitative real-time polymerase chain reaction technology.
Academic Article	Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center.
Academic Article	Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia.
Academic Article	Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection.
Academic Article	AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.
Academic Article	Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens.
Academic Article	Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia.
Academic Article	A phase 2 study of yttrium-90 ibritumomab tiuxetan (Zevalin) in patients with chronic lymphocytic leukemia.
Academic Article	Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
Academic Article	Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.
Academic Article	Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Academic Article	LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.
Academic Article	Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease.
Academic Article	The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.
Academic Article	Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia.
Academic Article	Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic leukemia.
Academic Article	Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia.
Academic Article	The prognostic difference of monoallelic versus biallelic deletion of 13q in chronic lymphocytic leukemia.
Academic Article	The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo.
Academic Article	Making advances in first-line chronic lymphocytic leukemia treatment.
Academic Article	Phase II study of lenalidomide and rituximab as salvage therapy for patients with relapsed or refractory chronic lymphocytic leukemia.
Academic Article	Lenalidomide induces long-lasting responses in elderly patients with chronic lymphocytic leukemia.
Academic Article	Statin and aspirin use is associated with improved outcome of FCR therapy in relapsed/refractory chronic lymphocytic leukemia.
Academic Article	Immunotherapy of chronic lymphocytic leukemia.
Academic Article	In vivo activation of signal transducer and activator of transcription 1 after CD154 gene therapy for chronic lymphocytic leukemia is associated with clinical and immunologic response.
Academic Article	Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia.
Academic Article	Genetics and molecular biology of chronic lymphocytic leukemia.
Academic Article	Evolution of treatment strategies in chronic lymphocytic leukemia. Part 2 of a 3-Part series: Advances in the treatment of hematologic malignancies.
Academic Article	Initial therapy for patients with chronic lymphocytic leukemia.
Academic Article	Pilot experience with continuous infusion alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia.
Academic Article	Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.
Academic Article	Other malignancies in chronic lymphocytic leukemia/small lymphocytic lymphoma.
Academic Article	Characteristics associated with important clinical end points in patients with chronic lymphocytic leukemia at initial treatment.
Academic Article	New prognostic factors in chronic lymphocytic leukemia.
Academic Article	De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience.
Academic Article	Chronic lymphocytic leukemia: treatment options for patients with refractory disease.
Academic Article	Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Academic Article	Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia.
Academic Article	p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy.
Academic Article	Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Alemtuzumab by continuous intravenous infusion followed by subcutaneous injection plus rituximab in the treatment of patients with chronic lymphocytic leukemia recurrence.
Academic Article	Richter's transformation in chronic lymphocytic leukemia.
Academic Article	Role of CD20 monoclonal antibodies in previously untreated chronic lymphocytic leukemia.
Academic Article	High serum thymidine kinase 1 level predicts poorer survival in patients with chronic lymphocytic leukemia.
Academic Article	Chronic lymphocytic leukemia: new concepts for future therapy.
Academic Article	Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.
Academic Article	Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration.
Academic Article	Azacitidine in fludarabine-refractory chronic lymphocytic leukemia: a phase II study.
Academic Article	Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia.
Academic Article	Myelosuppression after frontline fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: analysis of persistent and new-onset cytopenia.
Academic Article	Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors.
Academic Article	Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.
Academic Article	CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia.
Academic Article	Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients with Richter syndrome or fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP.
Academic Article	Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
Academic Article	Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years.
Academic Article	Investigational immunotherapeutics for B-cell malignancies.
Academic Article	Self-administered, subcutaneous alemtuzumab to treat residual disease in patients with chronic lymphocytic leukemia.
Academic Article	CCL3 (MIP-1a) plasma levels and the risk for disease progression in chronic lymphocytic leukemia.
Academic Article	Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia.
Academic Article	Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia.
Academic Article	A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Clinical characteristics, response to therapy, and survival of African American patients diagnosed with chronic lymphocytic leukemia: joint experience of the MD Anderson Cancer Center and Duke University Medical Center.
Academic Article	The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
Academic Article	Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Academic Article	CD40 activation does not protect chronic lymphocytic leukemia B cells from apoptosis induced by cytotoxic T lymphocytes.
Academic Article	A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens.
Academic Article	Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3.
Academic Article	Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia.
Academic Article	The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Academic Article	Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.
Academic Article	Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.
Academic Article	New aspects of the treatment of chronic lymphocytic leukemia.
Academic Article	Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia.
Academic Article	Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells.
Academic Article	Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
Academic Article	Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL).
Academic Article	Fludarabine, cyclophosphamide and rituximab plus granulocyte macrophage colony-stimulating factor as frontline treatment for patients with chronic lymphocytic leukemia.
Academic Article	Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia.
Academic Article	The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
Academic Article	Population pharmacokinetics of ofatumumab in patients with chronic lymphocytic leukemia, follicular lymphoma, and rheumatoid arthritis.
Academic Article	Outcomes of first-line treatment for chronic lymphocytic leukemia with 17p deletion.
Academic Article	Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia.
Academic Article	The use of obinutuzumab in chronic lymphocytic leukemia.
Academic Article	FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia.
Academic Article	Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy: distribution and clinical outcomes.
Academic Article	A phase II study of the combination of rituximab and granulocyte macrophage colony stimulating factor as treatment of patients with chronic lymphocytic leukemia.
Academic Article	Progress in novel cellular therapy options for chronic lymphocytic leukemia: the M D Anderson perspective.
Academic Article	Regulation of Mcl-1 expression in context to bone marrow stromal microenvironment in chronic lymphocytic leukemia.
Academic Article	Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells.
Academic Article	Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia.
Academic Article	Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib.
Academic Article	High fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic leukemia is an independent predictor of adverse outcome.
Academic Article	Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.
Academic Article	Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia: final results from a pivotal study.
Academic Article	Second cancers and Richter transformation are the leading causes of death in patients with trisomy 12 chronic lymphocytic leukemia.
Academic Article	Three newly approved drugs for chronic lymphocytic leukemia: incorporating ibrutinib, idelalisib, and obinutuzumab into clinical practice.
Academic Article	Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia.
Academic Article	Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure.
Academic Article	Updates to the management of chronic lymphocytic leukemia.
Academic Article	Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens.
Academic Article	Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia.
Academic Article	Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival.
Academic Article	Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia.
Academic Article	Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.
Academic Article	Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics.
Academic Article	Incidence and prognostic impact of other cancers in a population of long-term survivors of chronic lymphocytic leukemia.
Academic Article	High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia.
Academic Article	Second cancers and Richter transformation are the leading causes of death in patients with trisomy 12 chronic lymphocytic leukemia
Academic Article	ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2)
Academic Article	Refractory chronic lymphocytic leukemia
Academic Article	Fludarabine, cyclophosphamide, and rituximab treatment achieves long-Term disease-free survival in IGHV-mutated chronic lymphocytic leukemia
Academic Article	Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival
Academic Article	Three Newly Approved Drugs for Chronic Lymphocytic Leukemia
Academic Article	Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome
Academic Article	A phase II study of the combination of rituximab and granulocyte macrophage colony stimulating factor as treatment of patients with chronic lymphocytic leukemia
Academic Article	Salvage chemoimmunotherapy for patients with relapsed/refractory chronic lymphocytic leukemia
Academic Article	Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia
Academic Article	Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia
Academic Article	Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens
Academic Article	Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia
Academic Article	Minimal residual disease provides treatment focus for next chronic lymphocytic leukemia advances
Academic Article	Î²₂-microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia
Academic Article	Highlights of the 6th Young Investigators' Meeting on chronic lymphocytic leukemia
Academic Article	Incidence and prognostic impact of other cancers in a population of long-term survivors of chronic lymphocytic leukemia
Academic Article	Chronic lymphocytic leukemias
Academic Article	Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia
Academic Article	FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia
Academic Article	Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia
Academic Article	Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells
Academic Article	Pharmacological and protein profiling suggests venetoclax (ABT-199) as optimal partner with ibrutinib in chronic lymphocytic leukemia
Academic Article	At high levels, constitutively activated STAT3 induces apoptosis of chronic lymphocytic leukemia cells
Academic Article	Reactivation of smac-mediated apoptosis in chronic lymphocytic leukemia cells
Academic Article	Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib
Academic Article	Ofatumumab and lenalidomide for patients with relapsed or refractory chronic lymphocytic leukemia
Academic Article	Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia
Academic Article	A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia
Academic Article	Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy
Academic Article	Functional differences between IgM and IgD signaling in chronic lymphocytic leukemia
Academic Article	CD154 (CD40-LIGAND) gene therapy for chronic lymphocytic leukemia leads to in vivo activation of the stat1 signaling pathway
Academic Article	Carfilzomib triggers cell death in chronic lymphocytic leukemia by inducing proapoptotic and endoplasmic reticulum stress responses
Academic Article	B-cell Receptor Signaling Regulates Metabolism in Chronic Lymphocytic Leukemia.
Academic Article	Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy.
Academic Article	Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome.
Academic Article	Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells.
Academic Article	A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.
Academic Article	Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia.
Academic Article	Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib.
Academic Article	Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses.
Academic Article	At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells.
Academic Article	?2 -microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia.
Academic Article	Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia.
Academic Article	Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic.
Academic Article	Minimal Residual Disease Provides Treatment Focus for Next Chronic Lymphocytic Leukemia Advances.
Academic Article	Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab.
Academic Article	Outcomes of patients with chronic lymphocytic leukemia treated with first-line idelalisib plus rituximab after cessation of treatment for toxicity.
Academic Article	Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia.
Academic Article	ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2).
Academic Article	Extended Treatment with Single-Agent Ibrutinib at the 420 mg Dose Leads to Durable Responses in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Academic Article	Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia.
Academic Article	Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib.
Academic Article	Long-term Follow-up of Treatment with Ibrutinib and Rituximab in Patients with High-Risk Chronic Lymphocytic Leukemia.
Academic Article	Economic Burden of Chronic Lymphocytic Leukemia in the Era of Oral Targeted Therapies in the United States.
Academic Article	Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells.
Academic Article	Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia.
Academic Article	Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells.
Academic Article	Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.
Academic Article	Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199).
Academic Article	NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1.2017.
Academic Article	Activation of the B-cell receptor successively activates NF-?B and STAT3 in chronic lymphocytic leukemia cells.
Academic Article	Long-term outcomes for patients with chronic lymphocytic leukemia who discontinue ibrutinib.
Academic Article	Outcomes of adults with relapsed or refractory Burkitt and high-grade B-cell leukemia/lymphoma.
Academic Article	Consolidation treatment with lenalidomide following front-line or salvage chemoimmunotherapy in chronic lymphocytic leukemia.
Academic Article	The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells.
Academic Article	Proteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells.
Academic Article	Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Acute promyelocytic leukemia in a patient with chronic lymphocytic leukemia-A case report.
Academic Article	Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia.
Academic Article	Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia.
Academic Article	Sustained long-lasting responses after lenalidomide discontinuation in patients with chronic lymphocytic leukemia.
Academic Article	The CXCR4-STAT3-IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide.
Academic Article	Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide.
Academic Article	Single-agent ibrutinib in treatment-na?ve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience.
Academic Article	Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells.
Academic Article	STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells.
Academic Article	Comprehensive Safety Analysis of Venetoclax Monotherapy for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia.
Academic Article	Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial.
Academic Article	STAT3-activated CD36 facilitates fatty acid uptake in chronic lymphocytic leukemia cells.
Academic Article	NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019.
Academic Article	Targeted multigene deep sequencing of Bruton tyrosine kinase inhibitor-resistant chronic lymphocytic leukemia with disease progression and Richter transformation.
Academic Article	Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia.
Academic Article	Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia.
Academic Article	Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia.
Academic Article	Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy.
Academic Article	A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia.
Academic Article	Ofatumumab is safe and effective as front-line treatment in older patients with chronic lymphocytic leukemia and severe co-morbidities, including other malignancies.
Academic Article	Efficacy of venetoclax in relapsed chronic lymphocytic leukemia is influenced by disease and response variables.
Academic Article	PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells.
Concept	Myeloid Cell Leukemia Sequence 1 Protein
Academic Article	Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells.
Academic Article	Does FCR have the potential to cure a subgroup of patients with chronic lymphocytic leukemia?
Academic Article	Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia.
Academic Article	Targeting BCL2 in Chronic Lymphocytic Leukemia and Other Hematologic Malignancies.
Academic Article	Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia.
Academic Article	Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Academic Article	Ublituximab and umbralisib in relapsed/refractory B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Academic Article	STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage.
Academic Article	Evolving Strategies in First-Line Chronic Lymphocytic Leukemia: Is There a Role for Chemoimmunotherapy?
Academic Article	The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment.
Academic Article	Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results.
Academic Article	AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia.
Academic Article	Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Ibrutinib Treatment for First-Line and Relapsed/Refractory Chronic Lymphocytic Leukemia: Final Analysis of the Pivotal Phase Ib/II PCYC-1102 Study.
Academic Article	International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.
Academic Article	Incidence and characterization of fungal infections in chronic lymphocytic leukemia patients receiving ibrutinib.
Academic Article	Integrated Mechanistic Model of Minimal Residual Disease Kinetics With Venetoclax Therapy in Chronic Lymphocytic Leukemia.
Academic Article	Incidental Richter transformation in chronic lymphocytic leukemia patients during temporary interruption of ibrutinib.
Academic Article	CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia.
Academic Article	The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of action.
Academic Article	STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells.
Academic Article	Acalabrutinib in treatment-naive chronic lymphocytic leukemia.
Academic Article	Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations.
Academic Article	Ibrutinib Plus Venetoclax for First-line Treatment of Chronic Lymphocytic Leukemia: A Nonrandomized Phase 2 Trial.
Academic Article	Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations.
Academic Article	Vecabrutinib inhibits B-cell receptor signal transduction in chronic lymphocytic leukemia cell types with wild-type or mutant Bruton tyrosine kinase.
Academic Article	Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study.
Academic Article	RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences.
Academic Article	The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View.
Academic Article	Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis.
Academic Article	Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-na?ve chronic lymphocytic leukemia.
Academic Article	Lenalidomide enhances CD23.CAR T cell therapy in chronic lymphocytic leukemia.
Academic Article	Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.
Academic Article	Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures.
Academic Article	Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia.
Academic Article	Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells.
Academic Article	STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells.
Academic Article	Pirtobrutinib inhibits wild-type and mutant Bruton's tyrosine kinase-mediated signaling in chronic lymphocytic leukemia.
Academic Article	TP53-altered chronic lymphocytic leukemia treated with firstline Bruton's tyrosine kinase inhibitor-based therapy: A retrospective analysis.
Academic Article	NCCN Guidelines? Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022.
Academic Article	A review of the incidence of tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with venetoclax and debulking strategies.
Academic Article	Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.
Academic Article	Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies.
Academic Article	Reverse Phase Protein Array Profiling Identifies Recurrent Protein Expression Patterns of DNA Damage-Related Proteins across Acute and Chronic Leukemia: Samples from Adults and the Children's Oncology Group.
Academic Article	Prognostication of DNA Damage Response Protein Expression Patterns in Chronic Lymphocytic Leukemia.
Academic Article	Long-term outcomes in patients with chronic lymphocytic leukemia treated with ibrutinib: Focus on hypertension and cardiovascular toxicity.
Academic Article	Incidence of major bleeding in patients with chronic lymphocytic leukemia receiving ibrutinib and therapeutic anticoagulation.
Academic Article	Outcomes in Patients with High-Risk Features after Fixed-Duration Ibrutinib plus Venetoclax: Phase II CAPTIVATE Study in First-Line Chronic Lymphocytic Leukemia.
Academic Article	Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia.
Academic Article	Global miRNA profiling reveals key molecules that contribute to different chronic lymphocytic leukemia incidences in Asian and Western populations.
Academic Article	Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia.
Academic Article	Ibrutinib Plus Venetoclax for First-Line Chronic Lymphocytic Leukemia Treatment.
Academic Article	A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia.

Search Criteria

Leukemia T Cell